Two sample MR report
SELENOW_Endothelial Cell (Endo) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.0519197 | 0.3351148 | 0.8867126 |
| Weighted median | 5 | -0.1473962 | 0.0369233 | 0.0000655 |
| Inverse variance weighted | 5 | -0.1455693 | 0.0307869 | 0.0000023 |
| Simple mode | 5 | -0.1571696 | 0.0474154 | 0.0295234 |
| Weighted mode | 5 | -0.1325781 | 0.0460272 | 0.0449937 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1279685 | 3 | 0.9882818 |
| Inverse variance weighted | 0.2067285 | 4 | 0.9950122 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0428961 | 0.1528496 | 0.797226 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001781 | 0 | TRUE | 0.2071092 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
